Web seminars

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Open web seminar	Optimal selection of monoclonal cell lines producing high amounts of biopharmaceutical human IgGs. Jolanda Gerritsen, Technology Expert, Cell Line Development, Genmab, The Netherlands Genmab have optimized and integrated emerging technologies to achieve an optimal, state-of-the-art process for generation of CHO cell lines expressing therapeutic IgGs. Dr. Gerritsen explains how expression levels and quality were improved and time lines decreased by implementing a ClonePix™ system to select high expressing cell lines and enable fast clonal cell line generation. She also describes the integration of a μ-24 BioReactor as a high throughput bioreactor system to mimic the conditions of a standard bioreactor.
Open web seminar	Using non-invasive, image-based analysis to save time and improve consistency assessing cell growth Claudia Melara, Application Scientist Hear how CloneSelect™ Imager replaces time-consuming manual assessment of confluence and growth curves to obtain high quality cells for cell biology, biomedical research or drug screening.
Open web seminar	Using high throughput automated selection to increase discovery of rare, high producing mammalian cell lines. Suba Dharshanan, Inno Biologics and University of Malaya Medical Centre, Malaysia Dr Dharshanan presents how the use of ClonePix has increased the probability of finding rare high producing clones at Inno Biologics.
Open web seminar	CellReporter webinar: Accelerated high content screening and homogeneous quantification of soluble IgG levels Dr Alasdair Robertson, Head of Biology R&D, Genetix Limited Dr Robertson demonstrates how utilizing the CellReporter™ system's quantitative approach to assessing IgG levels can save time and simplify workflow compared to conventional methods such as FMAT®. Data was also be presented on how the high resolution imaging and cell-by-cell analysis of CellReporter benefits a variety of cell-based assays.
Open web seminar	Phenotypic screening using CellReporter to identify cures for the deadliest poison Dr. Tobin Dickerson, The Scripps Institute Dr Dickerson will discuss the development of a whole cell based assay for Botulinum neurotoxin (BoNT) inhibitors based on the new CellReporter^TM multi-application platform. CellReporter enabled multiplexing of their functional assay with other drug development filters such as cytotoxicity. This new approach allows them to efficiently triage lead compounds to optimize those that enter in vivo studies of BoNT intoxication.
Open web seminar	Efficient Single-cell Cloning for Mammalian Cell Protein Expression with ClonePix FL Dr. Cheng Liu, President and CEO, Eureka Therapeutics, Inc. Dr Liu discusses how ClonePix^TM FL has helped Eureka Technology save months of time and labor costs compared to traditional limiting dilution method. When used for sub-cloning of existing antibody-producing cell lines, they have seen improved single-cell clonality and often better expression levels. Please note, due to technical difficulties during the webinar the sound will not start until slide 5.
Open web seminar	The use of ClonePix FL to increase productivity in a research-based hybridoma facility Dr. Robin Barbour, Associate Director Elan Pharmaceuticals “We have implemented ClonePix FL to increase our fusion productivity by approximately 50%, while decreasing our time from fusion to stable clone by 50%” “We have been able to perform primary screening of fusions directly in the initial fusion plates, thus eliminating the need for time-consuming ELISA assays. We can also assess stability, ensure clonal status and determine highest producers in a single cloning step. We have been able to rescue unstable clones and increase productivity of certain hybridomas with minimal efforts.”