Cytogenetix FISH probes, M-FISH paints, whole chromosome paints, telomere, centromere, breakapart probes

CytoGenetix FISH reagents and kits are developed to provide bright, clear results. The probes are derived from flow-sorted chromosomes amplified by degenerate oligonucleotide-primed polymerase chain reaction (DOP-PCR). Benefits of DOP-PCR derived probes are:

Cot-1 free paint system for competitor free labeling
Good specificity; equal to or better than Cot-1
CyDye provide bright, intense signals, low non-specific binding, high photo stability, high water solubility,
and pH insensitivity

Probes are labeled with Cy3, FITC or with Biotin to allow the use of any streptavidin-coupled fluorochromes.

Human whole chromosome paints

Available ready-to-use or in 5x concentrate. Paint boxes contain enough single chromosome paint to perform three tests on each class.

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Human centromeric and telomeric probes

Available for single chromosome classes, common translocations or as Pan kits for all classes.

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Multicolor painting and banding kits

M-FISH and PrismFISH kits for human and mouse. M-FISH kits contain kit contains a set of whole chromosome specific paints combinatorially labeled with FITC, Cy3, Cy3.5, Cy5 and Cy5.5. A filter set for these fluorochromes and an imaging system with M-FISH analysis software is required to analyze the cells.

PrismFISH is a quick and easy alternative to M-FISH. Each test paints a subset of chromosomes; six for human chromosomes (1-6, 7-12, 13-18, and 16-Y) and seven for mouse (1-7, 8-14, 15-Y). Visualize the entire genome in three or four tests using normal FISH techniques. PrismFISH does not require any special software or filters for visualization.

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Mouse whole chromosome paints and centromeric probes

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Whole chromosome paints for additional species

A selection of whole chromosome-specific paints for porcine, bovine, canine, equine, rabbit, rat and feline cells.

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Amplification and detection kits and reagents

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The cyanine dyes in these products are manufactured on behalf of GE HealthcareBiosciences Corp. under exclusive license from Carnegie Mellon University and are covered by US Patent Number 5 268 486 and foreign equivalents and pending applications. Cy and CyDye are trademarks of GE Healthcare Limited.

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